Description
Recombinant Human EIF4E Protein | PKSH032410 | Gentaur US, UK & Europe Disrtribition
Synonyms: Eukaryotic translation initiation factor 4E;eIF-4E;eIF-4F 25 kDa subunit;mRNA cap-binding protein;EIF4E;EIF4EL1;EIF4F
Active Protein: N/A
Activity: Recombinant Human Eukaryotic Translation Initiation Factor 4E is produced by our E.coli expression system and the target gene encoding Met1-Val217 is expressed.
Protein Construction: Recombinant Human Eukaryotic Translation Initiation Factor 4E is produced by our E.coli expression system and the target gene encoding Met1-Val217 is expressed.
Fusion Tag:
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 25.1 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Eukaryotic translation initiation factor 4E is a 217 amino acids protein that belongs to the eukaryotic initiation factor 4E family. eIF4F is a multi-subunit complex, the composition of which varies with external and internal environmental conditions. It is composed of at least EIF4A, EIF4E and EIF4G1/EIF4G3. EIF4E is also known to interact with other partners.It can recognize and bind the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
Research Area: epigenetics and nuclear signal