Recombinant Human DYNLL1 Protein (His Tag) | PKSH032338

Recombinant Human DYNLL1 Protein (His Tag) | PKSH032338 | Gentaur US, UK & Europe Disrtribition

Synonyms: Dynein Light Chain 1 Cytoplasmic; 8 kDa Dynein Light Chain; DLC8; Dynein Light Chain LC8-Type 1; Protein Inhibitor of Neuronal Nitric Oxide Synthase; PIN; DYNLL1;DLC1; DNCL1; DNCLC1; HDLC1

Active Protein: N/A

Activity: Recombinant Human Cytoplasmic Dynein Light Chain 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly89 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Cytoplasmic Dynein Light Chain 1 is produced by our E.coli expression system and the target gene encoding Met1-Gly89 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 12.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 200mM NaCl, 1mM DTT, pH 8.0.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.

Research Area: Signal Transduction, Cell biology, Neuroscience, Cancer, epigenetics and nuclear signal, metabolism,