Description
Recombinant Human dUTPase Protein (His Tag) | PKSH032365 | Gentaur US, UK & Europe Disrtribition
Synonyms: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial; dUTPase; dUTP Pyrophosphatase; DUT
Active Protein: N/A
Activity: Recombinant Human Deoxyuridine 5'-Triphosphate Nucleotidohydrolase;Mitochondrial is produced by our E.coli expression system and the target gene encoding Met1-Asn164 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human Deoxyuridine 5'-Triphosphate Nucleotidohydrolase;Mitochondrial is produced by our E.coli expression system and the target gene encoding Met1-Asn164 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 20.0 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Reconstitution: Not Applicable
Background: Deoxyuridine 5'-Triphosphate Nucleotidohydrolase Mitochondrial (dUTPase) belongs to the dUTPase family. dUTPase exits as a homotrimer and is involved in nucleotide metabolism. dUTPase produces dUMP; the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. The dUTPase increase in PCR product yield; length and fidelity enables further down-stream applications. These effects make dUTPase useful in PCR fidelity and yield-sensitive applications. dUTPase is specific for dUTP and is critical for the fidelity of DNA replication and repair.
Research Area: N/A
