Description
Recombinant Human DTD1 Protein (His Tag) | PKSH032363 | Gentaur US, UK & Europe Disrtribition
Synonyms: D-tyrosyl-tRNA(Tyr) deacylase 1;DNA-unwinding element-binding protein B;DUE-B;Histidyl-tRNA synthase-related;DTD1;C20orf88; DUEB; HARS2
Active Protein: N/A
Activity: Recombinant Human D-tyrosyl-tRNA(Tyr) deacylase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro209 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human D-tyrosyl-tRNA(Tyr) deacylase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Pro209 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 24.5 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Reconstitution: Not Applicable
Background: D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defense mechanism against a harmful effect of D-tyrosine.
Research Area: Signal Transduction, epigenetics and nuclear signal, metabolism,
