Description
Recombinant Human DCXR Protein (His Tag) | PKSH032714 | Gentaur US, UK & Europe Disrtribition
Synonyms: L-Xylulose Reductase; XR; Carbonyl Reductase II; Dicarbonyl/L-Xylulose Reductase; Kidney Dicarbonyl Reductase; kiDCR; Sperm Surface Protein P34H; DCXR
Active Protein: N/A
Activity: Recombinant Human L-Xylulose Reductase is produced by our E.coli expression system and the target gene encoding Met1-Cys244 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human L-Xylulose Reductase is produced by our E.coli expression system and the target gene encoding Met1-Cys244 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 28.1 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 1mM DTT, 30% Glycerol, 1mM DTT, pH 8.0.
Reconstitution: Not Applicable
Background: L-Xylulose Reductase is an enzyme that belongs to the Short-Chain Dehydrogenases/Reductases (SDR) family. L-Xylulose Reductase is responsible for the metabolism of Xylulose, converting it into Xylitol. L-Xylulose Reductase catalyzes the NADPH-dependent reduction of several Pentoses, Tetroses, Trioses, α-Dicarbonyl compounds and L-Xylulose. L-Xylulose Reductase participates in the Uronate Cycle of Glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing Xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.
Research Area: Signal Transduction, Cancer, metabolism,
