Description
Recombinant Human Cystatin C/CST3 Protein (His Tag) | PKSH033838 | Gentaur US, UK & Europe Disrtribition
Synonyms: Cys-C; CST3; Cystatin 3; ARMD11; Post-Gamma-Globulin
Active Protein: N/A
Activity: A DNA sequence encoding the Human Cys-C (P01034-1) (Ser27-Ala146) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the Human Cys-C (P01034-1) (Ser27-Ala146) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 13.3kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
Research Area: N/A
