Recombinant Human Cyr61/CCN1 Protein (Fc Tag) | PKSH032318

Recombinant Human Cyr61/CCN1 Protein (Fc Tag) | PKSH032318 | Gentaur US, UK & Europe Disrtribition

Synonyms: Protein CYR61;CCN family member 1; Cysteine-rich angiogenic inducer 61;Insulin-like growth factor-binding protein 10 ; GIG1; CYR61; CCN1;IGFBP10;

Active Protein: N/A

Activity: Recombinant Human Cysteine-rich angiogenic inducer 61 is produced by our Mammalian expression system and the target gene encoding Thr25-Asp381 is expressed with a Fc tag at the C-terminus.

Protein Construction: Recombinant Human Cysteine-rich angiogenic inducer 61 is produced by our Mammalian expression system and the target gene encoding Thr25-Asp381 is expressed with a Fc tag at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 66.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61, Insulin-like growth factor-binding protein 10, GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein and contains one CTCK (C-terminal cystine knot-like) domain, one IGFBP N-terminal domain, one TSP type-1 domain and one VWFC domain. CYR61 promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 plays important roles in inflammation and tissue repair. CYR61 is associated with diseases related to chronic inflammation, including rheumatoid arthritis, atherosclerosis, diabetes-related nephropathy and retinopathy, and many different forms of cancers.

Research Area: Signal Transduction, Cardiovascular, Cancer, immunology, Stem cells