Description
Recombinant Human Cyclophilin D/PPID Protein (His Tag) | PKSH032874 | Gentaur US, UK & Europe Disrtribition
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase D; PPIase D; 40 kDa Peptidyl-Prolyl Cis-Trans Isomerase; Cyclophilin-40; CYP-40; Cyclophilin-Related Protein; Rotamase D; PPID; CYP40; CYPD
Active Protein: N/A
Activity: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase D is produced by our E.coli expression system and the target gene encoding Met1-Ala370 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Protein Construction: Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase D is produced by our E.coli expression system and the target gene encoding Met1-Ala370 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.
Fusion Tag: N, C-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 43.9 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Reconstitution: Not Applicable
Background: Peptidyl-Prolyl Cis-Trans Isomerase D (PPID) belongs to the cyclophilin-type PPIase family and PPIase D subfamily. PPID is widely expressed and it contains one PPIase cyclophilin-type domain and three TPR repeats. PPID catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerates the folding of proteins. PPID can bind to the immunosuppressant cyclosporine A and is known that its overexpression suppresses the apoptosis in cancer cells.
Research Area: immunology
