Recombinant Human CTNNB1 Protein | PKSH500056

Recombinant Human CTNNB1 Protein | PKSH500056 | Gentaur US, UK & Europe Disrtribition

Synonyms: Catenin beta-1, Beta-catenin, CTNNB, OK, SW-cl.35, PRO2286

Active Protein: N/A

Activity: A DNA sequence encoding the Human Human CTNNB1 Protein(P35222)(131-670)was expressed with a polyhistidine tag at the N-terminus.

Protein Construction: A DNA sequence encoding the Human Human CTNNB1 Protein(P35222)(131-670)was expressed with a polyhistidine tag at the N-terminus.

Fusion Tag: N-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 59 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.

Research Area: Cancer, Cardiovascular, Neuroscience, Signal Transduction