Description
Recombinant Human CTGF/CCN2 Protein (Fc Tag) | PKSH032276 | Gentaur US, UK & Europe Disrtribition
Synonyms: Connective tissue growth factor;CCN family member 2;Hypertrophic chondrocyte-specific protein 24;Insulin-like growth factor-binding protein 8;CTGF;IGFBP8
Active Protein: N/A
Activity: Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Gln27-Ala349 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Human Connective tissue growth factor is produced by our Mammalian expression system and the target gene encoding Gln27-Ala349 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 62.6 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family; which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT); a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
Research Area: Cardiovascular, immunology
