Description
Recombinant Human Cryptic/CFC1 Protein (His Tag) | PKSH032287 | Gentaur US, UK & Europe Disrtribition
Synonyms: Cryptic protein;Cryptic family protein 1;CFC1
Active Protein: N/A
Activity: Recombinant Human Cryptic protein is produced by our Mammalian expression system and the target gene encoding Tyr26-Gly169 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Cryptic protein is produced by our Mammalian expression system and the target gene encoding Tyr26-Gly169 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 16.9 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Cryptic (CFC1) is a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family. It contains an EGF-like domain, and is glycosylated on its N-terminal during post-translational modification. Cryptic is identified as a NODAL coreceptor involved in the correct establishment of the left-right axis. It may play a role in mesoderm and/or neural patterning during gastrulation. The unnormal expression of this gene may causes a series of diseases such as HTX2, Transposition of the great arteries dextro-looped 2, and Conotruncal heart malformations.
Research Area: Signal Transduction,