Recombinant Human CLEC3B/Tetranectin Protein (His Tag) | PKSH032257

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SKU:
575-PKSH032257
€558.00
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Description

Recombinant Human CLEC3B/Tetranectin Protein (His Tag) | PKSH032257 | Gentaur US, UK & Europe Disrtribition

Synonyms: Tetranectin; TN; C-Type Lectin Domain Family 3 Member B; Plasminogen Kringle 4-Binding Protein; CLEC3B; TNA

Active Protein: N/A

Activity: Recombinant Human C-Type Lectin Domain Family 3 Member B is produced by our Mammalian expression system and the target gene encoding Glu22-Val202 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human C-Type Lectin Domain Family 3 Member B is produced by our Mammalian expression system and the target gene encoding Glu22-Val202 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 21.2 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: C-Type Lectin Domain Family 3 Member B (CLEC3B) is a serum and tissue protein and it contais a C-type lectin which binds to Ca++. CLEC3B is originally found in plasma, the concentrations approximately 10mg/l. It can bind to kringle 4 of plasminogen and enhance the activation of plaminogen to plasmin, catalyzed by tissue plasminogen activator in the presence of poly-D-lysine. In addition, CLEC3B may be involved in the packaging of molecules destined for exocytosis. Also, CLEC3B is best known as a prognostic marker in ovarian cancer.

Research Area: Signal Transduction, Cardiovascular,

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