Recombinant Human CDK2AP2 Protein (Human Cells, His Tag) | PKSH032232

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SKU:
575-PKSH032232
€535.00
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Description

Recombinant Human CDK2AP2 Protein (Human Cells, His Tag) | PKSH032232 | Gentaur US, UK & Europe Disrtribition

Synonyms: Cyclin-dependent kinase 2-associated protein 2;CDK2-associated protein 2;DOC-1-related protein;DOC-1R;CDK2AP2;DOC1R;p14

Active Protein: N/A

Activity: Recombinant Human Cyclin-Dependent Kinase 2-Associated Protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Thr126 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Cyclin-Dependent Kinase 2-Associated Protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Thr126 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 14.1 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: CDK2AP2; also known as DOC1R; is short for cyclin-dependent kinase 2-associated protein 2. The gene CDK2AP2 encodes this protein that interacts with cyclin-dependent kinase 2 associated protein 1. Pseudogenes associated with this gene are located on chromosomes 7 and 9. Alternatively spliced transcript variants have been observed for this gene. It belongs to the CDK2AP family. CDK2AP1 (cyclin-dependent kinase 2-associated protein 1); corresponding to the gene doc-1 (deleted in oral cancer 1); is a tumor suppressor protein. The doc-1 gene is absent or down-regulated in hamster oral cancer cells and in many other cancer cell types. The ubiquitously expressed CDK2AP1 protein is the only known specific inhibitor of CDK2; making it an important component of cell cycle regulation during G(1)-to-S phase transition.

Research Area: N/A

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