Recombinant Human Calumenin Protein (aa 20-315, His Tag) | PKSH033293

Recombinant Human Calumenin Protein (aa 20-315, His Tag) | PKSH033293 | Gentaur US, UK & Europe Disrtribition

Synonyms: Calumenin; Crocalbin; IEF SSP 9302; CALU

Active Protein: N/A

Activity: Recombinant Human Calumenin is produced by our Mammalian expression system and the target gene encoding Lys20-Phe315 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Calumenin is produced by our Mammalian expression system and the target gene encoding Lys20-Phe315 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 36.0 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expressed at high levels in the heart; placenta and skeletal muscle. Human Calumenin is synthesized as a 315 amino acid precursor that contains a 19 amino acid signal sequence; and a 296 amino acid mature chain. Calumenin localizes to the endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues which plays a role in ER functions as protein folding and sorting. Calumenin is involved in the regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit γ-carboxylase GGCX.

Research Area: N/A