Recombinant Human BPI/CAP57 Protein (His Tag) | PKSH032108

Recombinant Human BPI/CAP57 Protein (His Tag) | PKSH032108 | Gentaur US, UK & Europe Disrtribition

Synonyms: Bactericidal permeability-increasing protein;BPI;CAP57

Active Protein: N/A

Activity: Recombinant Human Bactericidal permeability-increasing protein is produced by our Mammalian expression system and the target gene encoding Val32-Lys487 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Bactericidal permeability-increasing protein is produced by our Mammalian expression system and the target gene encoding Val32-Lys487 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 52.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.

Research Area: Microbiology, Cardiovascular, immunology