Recombinant Human BMPR2 protein(His tag) | PKSH500098

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SKU:
575-PKSH500098
€525.00
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Description

Recombinant Human BMPR2 protein(His tag) | PKSH500098 | Gentaur US, UK & Europe Disrtribition

Synonyms: BMP type-2 receptor;BMPR-2;Bone morphogenetic protein receptor type II;BMP type II receptor;BMPR-II

Active Protein: N/A

Activity: A DNA sequence encoding theHuman BMPR2 protein (Q13873) (Ser27-Thr150) was expressed with a N-His.

Protein Construction: A DNA sequence encoding theHuman BMPR2 protein (Q13873) (Ser27-Thr150) was expressed with a N-His.

Fusion Tag: N-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 26 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Research Area: N/A

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