Description
Recombinant Human BLVRA Protein (His Tag) | PKSH032118 | Gentaur US, UK & Europe Disrtribition
Synonyms: BLVRA;Biliverdin reductase A;BVR A;Biliverdin-IX alpha-reductase;BLVR;BVR
Active Protein: N/A
Activity: Recombinant Human Biliverdin reductase A is produced by our E.coli expression system and the target gene encoding Glu6-Ser294 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Biliverdin reductase A is produced by our E.coli expression system and the target gene encoding Glu6-Ser294 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 33.8 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 0.05% Brij35, 20%Glycerol, pH 8.0.
Reconstitution: Not Applicable
Background: Human Biliverdin reductase A (BLVRA) is belonged to the Gfo/Idh/MocA family and Biliverdin reductase subfamily. BLVRA is an enzyme that in humans is encoded by the BLVRA gene. BLVRA plays an important role in reducing the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor. BLVRA acts on biliverdin by reducing its double-bond between the pyrrole rings into a single-bond. It accomplishes this using NADPH + H+ as an electron donor, forming bilirubin and NADP+ as products.
Research Area: Signal Transduction, Cell biology, metabolism,
