Description
Recombinant Human BLBP/FABP7 Protein | PKSH030813 | Gentaur US, UK & Europe Disrtribition
Synonyms: Fatty Acid-Binding Protein Brain; Brain Lipid-Binding Protein; BLBP; Brain-Type Fatty Acid-Binding Protein; B-FABP; Fatty Acid-Binding Protein 7; Mammary-Derived Growth Inhibitor Related; FABP7; BLBP; FABPB; MRG
Active Protein: N/A
Activity: A DNA sequence encoding the mature form of human FABP7 (O15540) (Met1-Ala132) was expressed.
Protein Construction: A DNA sequence encoding the mature form of human FABP7 (O15540) (Met1-Ala132) was expressed.
Fusion Tag:
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 14.9 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: BLBP; also known as FABP7; is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small; highly conserved; cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake; transport; and metabolism. BLBP is expressed; during development; in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition(PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.
Research Area: Signal Transduction, Neuroscience, Cancer, metabolism,
