Recombinant Human BDNF protein(His tag) | PKSH500073

Recombinant Human BDNF protein(His tag) | PKSH500073 | Gentaur US, UK & Europe Disrtribition

Synonyms: Abrineurin;ProBDNF

Active Protein: N/A

Activity: A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.

Protein Construction: A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.

Fusion Tag: C-His

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 26 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Research Area: N/A