Description
Recombinant Human BDH1 Protein (His Tag) | PKSH032366 | Gentaur US, UK & Europe Disrtribition
Synonyms: D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial; BDH; 3-Hydroxybutyrate Dehydrogenase; BDH
Active Protein: N/A
Activity: Recombinant Human D-beta-Hydroxybutyrate Dehydrogenase Mitochondrial/BDH1 is produced by our E.coli expression system and the target gene encoding Met1-Arg343 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human D-beta-Hydroxybutyrate Dehydrogenase Mitochondrial/BDH1 is produced by our E.coli expression system and the target gene encoding Met1-Arg343 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 40.3 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 1mM DTT, pH 7.5.
Reconstitution: Not Applicable
Background: D-Beta-Hydroxybutyrate Dehydrogenase Mitochondrial (BDH) is a member of the short-chain dehydrogenases/reductases (SDR) family. BDH is localized in the mitochondrion matrix. BDH forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific necessity for phosphatidylcholine for optimal enzymatic activity. BDH catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the 2 main ketone bodies formed during fatty acid catabolism.
Research Area: Signal Transduction, Cancer, metabolism,
