Recombinant Human BAG2 Protein (His Tag) | PKSH032114

Recombinant Human BAG2 Protein (His Tag) | PKSH032114 | Gentaur US, UK & Europe Disrtribition

Synonyms: BAG Family Molecular Chaperone Regulator 2; BAG-2; Bcl-2-Associated Athanogene 2; BAG2

Active Protein: N/A

Activity: Recombinant Human BAG Family Molecular Chaperone Regulator 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn211 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human BAG Family Molecular Chaperone Regulator 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn211 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 25.9 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.

Reconstitution: Please refer to the printed manual for detailed information.

Background: BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Research Area: Signal Transduction, Cell biology, Cancer, metabolism,