Description
Recombinant Human ASGR1/ASGPR1 Protein (His Tag) | PKSH033403 | Gentaur US, UK & Europe Disrtribition
Synonyms: Asialoglycoprotein Receptor 1; ASGP-R 1; ASGPR 1; C-Type Lectin Domain Family 4 Member H1; Hepatic Lectin H1; HL-1; ASGR1; CLEC4H1
Active Protein: N/A
Activity: Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Asialoglycoprotein Receptor 1 is produced by our Mammalian expression system and the target gene encoding Gln62-Ile291 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 27.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor; belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits; ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins; recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1; results in the complex is internalized and transported to a sorting organelle; then ASGPR1 and ligand can be disassociated; ASGPR1 returns to the cell membrane surface.
Research Area: Signal Transduction, Tags & Cell Markers,
