Recombinant Human ASB13 Protein (His Tag) | PKSH032070

Recombinant Human ASB13 Protein (His Tag) | PKSH032070 | Gentaur US, UK & Europe Disrtribition

Synonyms: Ankyrin repeat and SOCS box protein 13; ASB13;

Active Protein: N/A

Activity: Recombinant Human Ankyrin repeat and SOCS box protein 13 is produced by our E.coli expression system and the target gene encoding Met1-Asn278 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Ankyrin repeat and SOCS box protein 13 is produced by our E.coli expression system and the target gene encoding Met1-Asn278 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 31.4 kDa

Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea.

Reconstitution: Not Applicable

Background: Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

Research Area: Cell biology