Description
Recombinant Human Arylsulfatase A/ARSA Protein (His Tag) | PKSH032093 | Gentaur US, UK & Europe Disrtribition
Synonyms: Arylsulfatase A; ASA; Cerebroside-Sulfatase; ARSA
Active Protein: N/A
Activity: Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Arylsulfatase A is produced by our Mammalian expression system and the target gene encoding Arg19-Ala507 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 52.9 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5.
Reconstitution: Not Applicable
Background: Arylsulfatase A (ARSA) is a lysosomal enzyme that breaks down Cerebroside 3-Sulfate, a major constituent of the myelin sheet, into Cerebroside and Sulfate. The ARSA deficiency results in Metachromatic Leukodystrophy (MLD), a lysosomal storage disease in the central and peripheral nervous systems with severe and progressive neurological symptoms. Recombinant Human ARSA corresponds to the ARSA mature peptide and has sulfatase activity.
Research Area: Signal Transduction, Tags & Cell Markers, Cell biology, Neuroscience, Cancer, metabolism,
