Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag) | PKSH032084

Recombinant Human Apolipoprotein C-II/APOC2 Protein (His Tag) | PKSH032084 | Gentaur US, UK & Europe Disrtribition

Synonyms: Apolipoprotein C-II; Apolipoprotein C2; APC2 and APOC2

Active Protein: N/A

Activity: Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Apolipoprotein C-II is produced by our E.coli expression system and the target gene encoding Met1-Glu82 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 10.0 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mMPB, 150mM NaCL, 30%glycerol, pH7.2.

Reconstitution: Not Applicable

Background: APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoproteinemia type 1B (HLPP1B) which characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.

Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,