Description
Recombinant Human AMIGO2 Protein (aa 1-398, His Tag) | PKSH030569 | Gentaur US, UK & Europe Disrtribition
Synonyms: Amphoterin-Induced Protein 2; AMIGO-2; Alivin-1; Differentially Expressed in Gastric Adenocarcinomas; DEGA; ALI1
Active Protein: N/A
Activity: A DNA sequence encoding the human AMIGO2 (NP_862830.1) (Met1-Thr398) was expressed with a polyhistidine tag at the C-terminus.
Protein Construction: A DNA sequence encoding the human AMIGO2 (NP_862830.1) (Met1-Thr398) was expressed with a polyhistidine tag at the C-terminus.
Fusion Tag: C-His
Species: Human
Expressed Host: HEK293 Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 42.3 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: AMIGO2 contains Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. It belongs to the immunoglobulin superfamily, AMIGO family. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. It is required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may also contribute to signal transduction through its intracellular domain. It may play a role in the tumorigenesis of a subset of gastric adenocarcinomas. AMIGO2 is highly expressed in breast, ovary, cervix, and uterus.
Research Area: Neuroscience
