Description
Recombinant Human Alpha-Parvin/PARVA Protein (His Tag) | PKSH033252 | Gentaur US, UK & Europe Disrtribition
Synonyms: Alpha-Parvin; Actopaxin; CH-ILKBP; Calponin-Like Integrin-Linked Kinase-Binding Protein; Matrix-Remodeling-Associated Protein 2; PARVA; MXRA2
Active Protein: N/A
Activity: Recombinant Human alpha-Parvin is produced by our E.coli expression system and the target gene encoding Met1-Glu372 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human alpha-Parvin is produced by our E.coli expression system and the target gene encoding Met1-Glu372 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 43.2 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 50mM Tris, 150mM NaCl, 40% Glycerol, pH 7.4.
Reconstitution: Not Applicable
Background: Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
Research Area: Signal Transduction,
