Recombinant Human ALDH1A3 Protein (His Tag) | PKSH033774

Recombinant Human ALDH1A3 Protein (His Tag) | PKSH033774 | Gentaur US, UK & Europe Disrtribition

Synonyms: Aldehyde dehydrogenase family 1 member A3; ALDH1A3; Aldehyde dehydrogenase 6; Retinaldehyde dehydrogenase 3; RALDH-3; ALDH6;ALDH1A6;MCOP8;RALDH3

Active Protein: N/A

Activity: Recombinant Human ALDH1A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human ALDH1A3 is produced by our E.coli expression system and the target gene encoding Met1-Pro512 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 57.5 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mMNaCl, pH7.5, 20% Glycerol.

Reconstitution: Not Applicable

Background: Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.

Research Area: Signal Transduction, Neuroscience, metabolism,