Description
Recombinant Human AKT2/PKB beta Protein (His & GST Tag) | PKSH030382 | Gentaur US, UK & Europe Disrtribition
Synonyms: HIHGHH;PKBB;PKBBETA;PRKBB;RAC-BETA
Active Protein: N/A
Activity: A DNA sequence encoding the human AKT2 (NP_001617.1) (Met1-Glu481) was expressed with a C-terminal polyhistidine-tagged GST tag at the N-terminus (his-GST).
Protein Construction: A DNA sequence encoding the human AKT2 (NP_001617.1) (Met1-Glu481) was expressed with a C-terminal polyhistidine-tagged GST tag at the N-terminus (his-GST).
Fusion Tag: N-His & GST
Species: Human
Expressed Host: Baculovirus-Insect Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 83.6 kDa
Formulation: Supplied as sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
Reconstitution: Not Applicable
Background: AKT2 (AKT Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with AKT2 include Hypoinsulinemic Hypoglycemia With Hemihypertrophy and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and RANK Signaling in Osteoclasts. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.
Research Area: Signal Transduction, Cardiovascular, Neuroscience, Cancer, metabolism,
