Description
Recombinant Human AKR1C2 Protein | PKSH032054 | Gentaur US, UK & Europe Disrtribition
Synonyms: Aldo-Keto Reductase Family 1 Member C2; 3-Alpha-HSD3; Chlordecone Reductase Homolog HAKRD; Dihydrodiol Dehydrogenase 2; DD-2; DD2; Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; DD/BABP; Trans-1;2-Dihydrobenzene-1;2-Diol Dehydrogenase; Type III 3-Alpha-Hydroxysteroid Dehydrogenase; AKR1C2; DDH2
Active Protein: N/A
Activity: Recombinant Human Aldo-Keto Reductase Family 1 Member C2 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed.
Protein Construction: Recombinant Human Aldo-Keto Reductase Family 1 Member C2 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed.
Fusion Tag:
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 36.7 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, pH 8.0.
Reconstitution: Not Applicable
Background: Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol).
Research Area: Signal Transduction, Cancer, metabolism,
