Recombinant FKBP52 Monoclonal Antibody | E-AB-81469

Recombinant FKBP52 Monoclonal Antibody | E-AB-81469 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Isotype: IgG

Application: WB, IF

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs, and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics, FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's, and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function, and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition, FKBP52 is likely to play a role in growth and development of the male genitalia.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:1000-1:5000 IF 1:20-1:50

Conjugation: Unconjugated

Calculated Molecular Weight: 52kDa

Observed Molecular Weight: 52kDa

Clonality: Rabbit Monoclonal