Recombinant Cofilin Monoclonal Antibody | E-AB-81548

Recombinant Cofilin Monoclonal Antibody | E-AB-81548 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P, IF

Research Area: Cancer, Cardiovascular, Neuroscience, Signal Transduction

Background: Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility, cytokinesis, and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity, also causing translocation from the nucleus to the cytoplasm.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 19kDa

Observed Molecular Weight: 19kDa

Clonality: Rabbit Monoclonal