Recombinant CLSTN1 Monoclonal Antibody | E-AB-81547

Recombinant CLSTN1 Monoclonal Antibody | E-AB-81547 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Hamster

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P

Research Area: N/A

Background: Calsyntenins (calsyntenin-1, -2, -3) compose a family of neuronally expressed proteins that belong to the cadherin superfamily of cell adhesion molecules (PMID: 24966372; 12498782). Calsyntenin-1 (CLSTN1) is a proteolytically processed postsynaptic membrane protein with a cytoplasmic calcium-binding domain. By binding Ca2+, calsyntenin-1 may modulate Ca2+-mediated postsynaptic signals (PMID: 11161476). Calsyntenin-1 is a transmembrane cargo-docking protein for Kinesin-1-mediated vesicular transport (PMID: 16760430). It can mediate axonal transport of the amyloid precursor protein and regulate Aβ production

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:500-1:1000 IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 110kDa

Observed Molecular Weight: 110kDa

Clonality: Rabbit Monoclonal