Description
Recombinant Angiotensin II Type 1 Receptor Monoclonal Antibody | E-AB-81528 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human
Host: Rabbit
Isotype: IgG
Application: WB
Research Area: Cancer, Cardiovascular, Metabolism
Background: Angiotensin II (Ang II), the main effector molecule of the renin-angiotensin system, exerts its actions mainly via interaction with type-1 angiotensin II receptor (AGTR1, also named as AT1R), thereby contributing to blood pressure regulation. AGTR1 mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. By regulating vascular tone, cardiovascular function, salt and water homeostasis, AGTR1 exerts an indispensable physiological role . AGTR1 has been implicated in diverse aspects of human disease, from the regulation of blood pressure and cardiovascular homeostasis to cancer progression .
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: N/A
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Dilution: WB 1:1000-1:2000
Conjugation: Unconjugated
Calculated Molecular Weight: 41kDa
Observed Molecular Weight: 41kDa
Clonality: Rabbit Monoclonal
