Description
Recombinant 4E BP1 Monoclonal Antibody | E-AB-81520 | Gentaur US, UK & Europe Disrtribition
Reactivity: Human, Mouse, Rat, Hamster
Host: Rabbit
Isotype: IgG
Application: WB, IHC-P
Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism
Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Lead Time: 7~10 days
Concentration: 300 μg/mL
Storage: Store at -20℃. Avoid freeze / thaw cycles.
Immunogen: N/A
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Dilution: WB 1:500-1:1000 IHC 1:50-1:100
Conjugation: Unconjugated
Calculated Molecular Weight: 13kDa
Observed Molecular Weight: 15/20kDa
Clonality: Rabbit Monoclonal
