Recombinant 4E BP1 Monoclonal Antibody | E-AB-81520

Recombinant 4E BP1 Monoclonal Antibody | E-AB-81520 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat, Hamster

Host: Rabbit

Isotype: IgG

Application: WB, IHC-P

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism

Background: Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.

Lead Time: 7~10 days

Concentration: 300 μg/mL

Storage: Store at -20℃. Avoid freeze / thaw cycles.

Immunogen: N/A

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification: Affinity Purified

Dilution: WB 1:500-1:1000 IHC 1:50-1:100

Conjugation: Unconjugated

Calculated Molecular Weight: 13kDa

Observed Molecular Weight: 15/20kDa

Clonality: Rabbit Monoclonal