RBPJ Antibody | F45603-0.08ML

RBPJ Antibody | F45603-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, IF, ELISA

Buffer: N/A

Limitation: This RBPJ antibody is available for research use only.

Purity: Antigen affinity

Description: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.

Immunogen: A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.

Storage: Aliquot the RBPJ antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.