Description
Rat PTK7 / CCK4 Protein, Fc Tag | PT7-R5255-100ug| Gentaur Distribution US, UK & Europe
PTK7, highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Source: Rat PTK7, Fc Tag (PT7-R5255) is expressed from human 293 cells (HEK293). It contains AA Ala 23 - Gln 695 (Accession # NP_001382670.1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Ala 23 - Gln 695.
Conjugate: Unconjugated.
Molecular Weight: 100.7 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 100.7 kDa. The protein migrates as 120-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT
