Rat Osteoblast | CP-R091

Rat Osteoblast | CP-R091 | Gentaur US, UK & Europe Disrtribition

Abbreviation: R-Ost

Organism: Rat

Tissue Type: Skeletal system

Tissue: Skull tissue

Cell Type: Osteocyte

Growth Proprieties: Adherent

Medium: CM-R091

Ratio: 1:2-1:3

Renwal: Every 2-3 days

Background: Rat osteoblasts were isolated from skull tissue. The skull is located above the spine and consists of 23 flat and irregular bones of different shapes and sizes. Except for the mandible and hyoid bone, the other bones are firmly connected to each other by seams or cartilage, which play a role in protecting and supporting the brain, sensory organs, and the starting part of the digestive organs and respirators. The skull is divided into two parts: the skull and the face. The brain is located in the upper part of the back of the skull, and there is a cranial cavity inside to accommodate the brain, a total of 8 pieces. The face is the anterior and lower part of the skull, including the orbit, nasal cavity, oral cavity and other structures, constituting the stent of the face, a total of 15 pieces. Osteoblasts are the main functional cells for bone formation and are responsible for the synthesis, secretion and mineralization of bone matrix. Bone is constantly undergoing reconstruction. The process of bone reconstruction includes osteoclasts attaching to the old bone area, secreting acidic substances to dissolve minerals, secreting proteases to digest bone matrix, and forming bone resorption lacuna. After that, osteoblasts migrate to the resorbed site, secrete bone matrix, and the bone matrix is mineralized to form new bone. The balance between osteoclast and osteogenic process is the key to maintaining normal bone mass. Osteoblast culture not only helps to understand the bone formation mechanism, the molecular and cytological basis of skeletal system diseases, but also an important method for drug screening, biomaterial development and bioengineering research. The rat osteoblasts produced by our company are prepared by first digesting with trypsin for a short time and then repeatedly digesting with collagenase. The total number of cells is about 5×10^5 cells/vial. The cells are identified by alkaline phosphatase staining and Alizarin Red staining, and the purity is more than 90% without HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi, etc.

Delivery: 4 weeks