Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified) | NC4-R5258-1mg

Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (MALS verified) | NC4-R5258-1mg| Gentaur Distribution US, UK & Europe

CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. NKG2A/CD159a is a transmembrane protein belonging to the CD94/NKG2 family of C-type lectin-like receptors that inhibits innate immune system activation. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA) -E on target cells.

Source: Rat NKG2A&CD94 Protein, Mouse IgG2a Fc Tag (NC4-R5258) is expressed from human 293 cells (HEK293). It contains AA Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94) (Accession # O54872-1 (NKG2A) & O35778-1 (CD94) ).

Format: Powder.

Tag: C-mFc (mIgG2a).

Expression System: HEK293.

Expression Region: Thr 90 - Asn 231 (NKG2A) & Lys 32 - Thr 179 (CD94).

Conjugate: Unconjugated.

Molecular Weight: 61.0 kDa.

Characteristics: This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 61.0 kDa. The protein migrates as 67-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT