Description
Rat Klotho beta / KLB Protein, His Tag | KLB-R52H6-100ug| Gentaur Distribution US, UK & Europe
KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.
Source: Rat Klotho beta, His Tag (KLB-R52H6) is expressed from human 293 cells (HEK293). It contains AA Phe 53 - Pro 994 (Accession # D3Z8T6-1).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Phe 53 - Pro 994.
Conjugate: Unconjugated.
Molecular Weight: 110.5 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 110.5 kDa. The protein migrates as 130-145 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
