Rat Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free | IT1-R53W5-100ug

Rat Integrin alpha V beta 1 (ITGAV&ITGB1) Heterodimer Protein, His Tag&Tag Free | IT1-R53W5-100ug| Gentaur Distribution US, UK & Europe

Integrin alpha-5/beta-1 is a receptor for ibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-V/beta-1 is also a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro). When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition.

Source: Rat ITGAV&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-R53W5) is expressed from CHO cells. It contains AA Phe 31 - Pro 988 & Gln 21 - Asp 729 (Accession # NP_001385621.1 & P49134-1).

Format: Powder.

Tag: C-10×His | Native.

Expression System: CHO.

Expression Region: Phe 31 - Pro 988 & Gln 21 - Asp 729.

Conjugate: Unconjugated.

Molecular Weight: 112.3 kDa & 83.7 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 112.3 kDa & 83.7 kDa. The protein migrates as 120-160 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50mM Tris, 150mM NaCl, PH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT