Description
Rage Antibody | F43706-0.08ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Antigen affinity purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse
Application: WB, ELISA
Buffer: N/A
Limitation: This Rage antibody is available for research use only.
Purity: Antigen affinity
Description: RAGE, the 'receptor for advanced glycation endproducts' is a transmembrane receptor of the immunoglobulin super family. The interaction between RAGE and its ligands, AGE and HMGB1, is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. [Wiki]
Immunogen: A portion of amino acids 76-104 from the mouse protein was used as the immunogen for this Rage antibody.
Storage: Aliquot the Rage antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
