Description
Rabbit CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc, low endotoxin (MALS verified) | CDD-R5259-1mg| Gentaur Distribution US, UK & Europe
T-cell surface glycoprotein CD3 delta & CD3 epsilon chain, also known as CD3D & CD3E or CD3D&CD3E respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Source: Rabbit CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc (CDD-R5259) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Thr 120 (CD3E) & Thr 22 - Ser 107 (CD3D) (Accession # Q9TUF9-1 (CD3E) & A0A5F9D3I4-1 (CD3D) ).
Format: Powder.
Tag: C-LlamaFc (LlamaIgG2b) | C-LlamaFc (LlamaIgG2b).
Expression System: HEK293.
Expression Region: Gln 22 - Thr 120 (CD3E) & Thr 22 - Ser 107 (CD3D).
Conjugate: Unconjugated.
Molecular Weight: 42.4 kDa (CD3E) & 40.8 kDa (CD3D).
Characteristics: Rabbit CD3E&CD3D Heterodimer Protein, Llama Fc&Llama Fc is produced by co-expression of CD3E and CD3D, has a calculated MW of 42.4 kDa (CD3E) and 40.8 kDa (CD3D). Subunit CD3E is fused with a llama IgG2b Fc tag at the C-terminus and subunit CD3D is fused with a llama IgG2b Fc tag at the C-terminus. The reducing (R) protein migrates as 50 kDa and 60 kDa due to glycosylation.
Purity: 95%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT