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Description
PYR-41 | 27716-1 | Gentaur US, UK & Europe Disrtribition
Category: Ubiquitination/Inhibitors / Activators
Application: Useful for inhibition of E1 ubiquitin conjugating enzymes
Background: N/A
Description: PYR-41 is a cell permeable, irreversible inhibitor of ubiquitin activating enzyme E1 with little or no activity against E2s or E3s (IC50 < 10 µM). It blocks degradation of p53 and inhibits NF-κappaB-dependent pathways. PYR-41 also increases SUMOylation of proteins.
Product Type: Inhibitors/Activators
Shippement Condition: room temp or gel packs
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