PVRIG: Nectin2 Inhibitor Screening ELISA Kit | EP-122-96tests

PVRIG: Nectin2 Inhibitor Screening ELISA Kit | EP-122| Gentaur Distribution US, UK & Europe

Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Source: Human PVRIG (poliovirus receptor related immunoglobulin domain-containing protein), also known as CD112 receptor (CD112R), is an approximately 34 kDa single transmembrane protein in the poliovirus receptor-like protein (PVR) family. The CD112R gene encodes a putative single transmembrane protein, which is composed of a single extracellular IgV domain, one transmembrane domain, and a long intracellular domain. Notably, the intracellular domain of phatases. The extracellular domain sequence of human and mouse CD112R have 65.3% similarity. CD112R may act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals.

Molecule: PVRIG.

Format: Solid.

Species: Human.

Application: This kit is developed for screening for inhibitors of human Nectin-2 binding to human PVRIG.

Kit Component: This inhibitor screening ELISA kit is designed to facilitate the identification and characterization of new PVRIG pathway inhibitors. The assay takes advantage of our in house-developed binding of biotinylated human Nectin-2 to immobilized human PVRIG in a functional ELISA assay, and employs a simple colorimetric ELISA platform. Briefly, we provide you with a human Biotinylated Nectin-2 protein, a human PVRIG protein, an anti-PVRIG neutralizing antibody (as method verified Std.), and Streptavidin-HRP reagent.

Stability: The unopened kit is stable for 12 months from the date of manufacture if stored at 2°C to 8°C. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

Storage Conditions: 2-8℃.

Shipping Conditions: RT