Purine nucleoside phosphorylase Antibody / PNP / Inosine phosphorylase | RQ6354

Purine nucleoside phosphorylase Antibody / PNP / Inosine phosphorylase | RQ6354 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Purified

Clone: 2H10

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Rat, Human

Application: WB

Buffer: Lyophilized from 1X PBS with 2% Trehalose

Limitation: This Purine nucleoside phosphorylase antibody is available for research use only.

Purity: Antigen affinity purified

Description: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.

Immunogen: Amino acids AMSDAYDRTMRQRALSTWKQMGEQRELQE were used as the immunogen for the Purine nucleoside phosphorylase antibody.

Storage: After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.