Description
Purine nucleoside phosphorylase Antibody / PNP / Inosine phosphorylase | RQ6354 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format: Purified
Clone: 2H10
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Rat, Human
Application: WB
Buffer: Lyophilized from 1X PBS with 2% Trehalose
Limitation: This Purine nucleoside phosphorylase antibody is available for research use only.
Purity: Antigen affinity purified
Description: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised T?lymphocyte function and neurologic dysfunction.
Immunogen: Amino acids AMSDAYDRTMRQRALSTWKQMGEQRELQE were used as the immunogen for the Purine nucleoside phosphorylase antibody.
Storage: After reconstitution, the Purine nucleoside phosphorylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.
