Description
Purified Anti-Mouse CD119 Antibody | DL21412F-2 | Gentaur US, UK & Europe Disrtribition
Synonyms: Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119
Reactivity: Mouse
Host: Rat
Application: FCM
Background: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
Concentration: 0.5 mg/mL
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Isotype: Rat IgG2a, κ
Storage: Store at 2~8°C. Do not freeze.
