Description
Purified Anti-Human CD28 Antibody | DL22136F-2 | Gentaur US, UK & Europe Disrtribition
Synonyms: PAS2,MNS,HGpMiX,GYPA,GPSAT
Reactivity: Human
Host: Mouse
Application: FCM
Background: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Concentration: 0.5 mg/mL
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Isotype: Mouse IgG1, κ
Storage: Store at 2~8°C. Do not freeze.
