Description
Purified Anti-Human CD16 Antibody | DL20200F-1 | Gentaur US, UK & Europe Disrtribition
Synonyms: Low affinity immunoglobulin gamma Fc region receptor III-A,FCGR3A,CD16a antigen,Fc-gamma RIII-alpha,Fc-gamma RIII,Fc-gamma RIIIa,FcRIII,FcRIIIa,FcR-10,IgG Fc receptor III-2,CD16a
Reactivity: Human
Host: Mouse
Application: FCM
Background: CD16 is known as low affinity IgG receptor III (FcγRIII) . It is expressed as two distinct forms (CD16a and CD16b) . CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans. CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI) -anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC) .
Concentration: 0.5 mg/mL
Conjugation: Unconjugated
Buffer: PBS with 0.05% Proclin300
Isotype: Mouse IgG1, κ
Storage: Store at 2~8°C. Do not freeze.
