Puma Antibody | F42785-0.4ML

Puma Antibody | F42785-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, IHC, IF, FACS, ELISA

Buffer: N/A

Limitation: This Puma antibody is available for research use only.

Purity: Purified

Description: PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Immunogen: A portion of amino acids 119-154 (BH3 domain) from the human protein was used as the immunogen for this Puma antibody.

Storage: Aliquot the Puma antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.